Publications

August 3, 2022

Mechanobiology of Metastasis in Bone

Sarazin BA, Ihle CL, Owens P, Lynch ME. “Mechanobiology of Metastasis in Bone.” Invited review to the ‘Biomechanics Section’ of Current Osteoporosis Reports. 19:580-591, 2021. doi.org/10.1007/s11914-021-00704-9.
January 27, 2021

Multiphysics simulation of a compression ‐ perfusion combined bioreactor to predict the mechanical microenvironment during bone metastatic breast cancer loading experiments

Liu B, Han S, Modarres-Sadeghi Y, Lynch ME. Multiphysics simulation of a compression – perfusion combined bioreactor to predict the mechanical microenvironment during bone metastatic breast cancer loading experiments. Biotechnology & Bioengineering. 118:1779-1792, 2021. doi:10.1002/bit.27692.
December 4, 2019

The Role of Mechanobiology in Cancer

Lynch ME, Neu CP, Seelbinder B, McCreery K (2019). “The Role of Mechanobiology in Cancer.” In Mechanobiological Basis of Diseases. New York, NY: Elsevier. ISBN 9780128179321.
November 9, 2019

Biomechanical Principles

McBride-Gagyi SH and Lynch ME (2019). “Biomechanical Principles.” In Essential Biomechanics for Orthopedic Trauma: A Case Based Guide. ISBN 978-3-030-36989-7.
May 20, 2019

Bone Mechanics in Cancer

Falk CH, Liu B, Lynch ME (2019). “Bone Mechanics in Cancer.” In Encyclopedia of Bone Biology: Cancer and Bone. doi.org/10.1016/B978-0-12-801238-3.11256-5.
December 26, 2018

Perfusion applied to a 3D model of bone metastasis results in uniformly dispersed mechanical stimuli

Liu, B, Han, S, Hedrick, BP, Modarres-Sadeghi, Y, & Lynch, ME (2018). “Perfusion applied to a 3D model of bone metastasis results in uniformly dispersed mechanical stimuli.” Biotechnology and Bioengineering. https://doi.org/10.1002/bit.26524.
July 3, 2018

Mechanically-Loaded Breast Cancer Cells Modify Osteocyte Mechanosensitivity by Secreting Factors That Increase Osteocyte Dendrite Formation and Downstream Resorption

Wang W, Sarazin BA, Kornilowicz G and Lynch ME (2018). “Mechanically-Loaded Breast Cancer Cells Modify Osteocyte Mechanosensitivity by Secreting Factors That Increase Osteocyte Dendrite Formation and Downstream Resorption.” Front. Endocrinol. https://doi.org/10.3389/fendo.2018.00352.
October 3, 2017

Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis

He, F, Chiou, AE, Loh, HC, Lynch, ME, Seo, BR, Song, YH, … Fischbach, C. (2017). “Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis.” Proceedings of the National Academy of Sciences, 114(40), 10542 LP-10547. https://doi.org/10.1073/pnas.1708161114.
August 1, 2016

3D mechanical loading modulates the osteogenic response of mesenchymal stem cells to tumor-derived soluble signals

Lynch ME, Chiou AE, Lee MJ, Polamraju P, Marcott SC, Lee Y, Fischbach C. “3D mechanical loading modulates the osteogenic response of mesenchymal stem cells to tumor-derived soluble signals.” Tissue Engineering Part A. 22:1006-15, 2016. doi:10.1089/ten.tea.2016.0153.