Our Research

3D CULTURE MODEL TO STUDY OSTEOCYTE MECHANOBIOLOGY. MECHANICAL LOADING ALTERS GENE EXPRESSION OF BONE METASTATIC BREAST CANCER CELLS MECHANICAL LOADING OF BONE PREVENTED BREAST CANCER CELLS FROM FORMING TUMORS FORCES RESULTING FROM PHYSICAL ACTIVITY AFFECT BEHAVIOR OF BONE AND CANCER CELLS PERFUSION APPLIED TO A 3D MODEL OF BONE METASTASIS RESULTS IN UNIFORMLY DISPERSED MECHANICAL STIMULI

Recent News

Latest Publications

January 27, 2021

Multiphysics simulation of a compression ‐ perfusion combined bioreactor to predict the mechanical microenvironment during bone metastatic breast cancer loading experiments

Liu B, Han S, Modarres-Sadeghi Y, Lynch ME. Multiphysics simulation of a compression – perfusion combined bioreactor to predict the mechanical microenvironment during bone metastatic breast cancer loading experiments. Biotechnol Bioeng. 2021 Jan 25. doi: 10.1002/bit.27692. Epub ahead of print. PMID: 33491767.
December 4, 2019

The Role of Mechanobiology in Cancer

Lynch ME, Neu CP, Seelbinder B, McCreery K (2019). “The Role of Mechanobiology in Cancer.” In Mechanobiological Basis of Diseases. New York, NY: Elsevier. ISBN 9780128179321.
November 9, 2019

Biomechanical Principles

McBride-Gagyi SH and Lynch ME (2019). “Biomechanical Principles.” In Essential Biomechanics for Orthopedic Trauma: A Case Based Guide. ISBN 978-3-030-36989-7.
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Get Involved!

The Lynch Lab is always interested in potential new lab members! Please contact Dr. Lynch to learn more about open projects.