Publications

Liu, B., Han, S., Hedrick, B. P., Modarres-Sadeghi, Y., & Lynch, M. E. (2018). “Perfusion applied to a 3D model of bone metastasis results in uniformly dispersed mechanical stimuli.” Biotechnology and Bioengineering. https://doi.org/10.1002/bit.26524

 

He, F., Chiou, A. E., Loh, H. C., Lynch, M. E., Seo, B. R., Song, Y. H., … Fischbach, C. (2017). “Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis.” Proceedings of the National Academy of Sciences, 114(40), 10542 LP-10547. https://doi.org/10.1073/pnas.1708161114

 

Lynch ME, Chiou AE, Lee MJ, Polamraju P, Marcott SC, Lee Y, Fischbach C. “3D mechanical loading modulates the osteogenic response of mesenchymal stem cells to tumor-derived soluble signals.” Tissue Engineering Part A. 22:1006-15, 2016. doi:10.1089/ten.tea.2016.0153.

 

Barney LE, Jansen LE, Polio SR, Galarza S, Lynch ME, Peyton SR. “The predictive link between matrix and metastasis.” Curr Opin Chem Eng. 11:85-93, 2016. doi.org/10.1016/j.coche.2016.01.001.

 

Lynch ME and Fischbach C. “Biomechanical forces in the skeleton and their relevance to bone metastasis: biology and engineering considerations.”  Advanced Drug Delivery Reviews, 79-80: 119-34, 2014. doi: 10.1016/j.addr.2014.08.009.

 

Main RP, Lynch ME, van der Meulen MCH. “Load-induced changes in bone stiffness and cancellous and cortical bone mass following tibial compression diminish with age in female mice.” The Journal of Experimental Biology, 217: 1775-83, 2014. doi: 10.1242/jeb.085522.

 

Lynch ME, Brooks DJ, Mohanan S, Lee MJ, Polamraju P, Dent KC, Bonassar L, van der Meulen MCH, Fischbach C. “In Vivo Tibial Compression Decreases Osteolysis and Tumor Formation in a Human Breast Cancer Metastasis Model.” Journal of Bone and Mineral Research, 28: 2357-2367, 2013. doi: 10.1002/jbmr.1966.

 

Infanger DW, Lynch ME, Fischbach C. “Engineered Culture Models for Studies of Tumor-Microenvironment Interactions.” Annual Review of Biomedical Engineering, 15: 29-53, 2013. doi: 10.1146/annurev-bioeng-071811-150028.

 

Lynch ME, Main RP, Xu Q, Schmicker TL, Schaffler MB, Wright TM, van der Meulen MCH. “Tibial Compression increases Cortical and Cancellous Bone Mass in Adult Female Mice.” Bone, 49: 439-46, 2010. doi: 10.1016/j.bone.2011.05.017.

 

Lynch ME, Main RP, Walsh DJ, Xu Q, Schaffler MB, Wright TM, van der Meulen MCH. “Cancellous bone adaptation to tibial compression is not sex-dependent in growing mice.” Journal of Applied Physiology, 109:685-691, 2010. doi: 10.1152/japplphysiol.00210.2010.

 

Main RP, Lynch ME, van der Meulen MCH. “In vivo tibial stiffness is maintained by whole bone morphology and cross-sectional geometry in growing female mice.” Journal of Biomechanics, 43:2689-2694, doi: 10.1016/j.jbiomech.2010.06.019.

 

Schnabel LV, Lynch ME, van der Meulen MCH, Yeager AC, Kornatowski MA, Nixon AJ. “Mesenchymal stem cells and insulin-like growth factor-I gene enhanced mesenchymal stem cells improve structural aspects of healing in equine flexor digitorum superficialis tendons.” Journal of Orthopaedic Research, 27: 1392-1398, 2009. doi: 10.1002/jor.20887.