Our Research

The shapes of thousands of osteocytes are measured in 3D via nanoCT. Collaboration with Virginia Ferguson. Live (green) and dead (red) staining demonstrates interconnected dendrites (arrows) MECHANICAL LOADING OF BONE PREVENTED BREAST CANCER CELLS FROM FORMING TUMORS Forces resulting from physical activity affect behavior of bone and cancer cells PERFUSION APPLIED TO A 3D MODEL OF BONE METASTASIS RESULTS IN UNIFORMLY DISPERSED MECHANICAL STIMULI

Recent News

Latest Publications

August 3, 2022

Mechanobiology of Metastasis in Bone

Sarazin BA, Ihle CL, Owens P, Lynch ME. “Mechanobiology of Metastasis in Bone.” Invited review to the ‘Biomechanics Section’ of Current Osteoporosis Reports. 19:580-591, 2021. doi.org/10.1007/s11914-021-00704-9.
January 27, 2021

Multiphysics simulation of a compression ‐ perfusion combined bioreactor to predict the mechanical microenvironment during bone metastatic breast cancer loading experiments

Liu B, Han S, Modarres-Sadeghi Y, Lynch ME. Multiphysics simulation of a compression – perfusion combined bioreactor to predict the mechanical microenvironment during bone metastatic breast cancer loading experiments. Biotechnology & Bioengineering. 118:1779-1792, 2021. doi:10.1002/bit.27692.
December 4, 2019

The Role of Mechanobiology in Cancer

Lynch ME, Neu CP, Seelbinder B, McCreery K (2019). “The Role of Mechanobiology in Cancer.” In Mechanobiological Basis of Diseases. New York, NY: Elsevier. ISBN 9780128179321.
parallax background

Get Involved!

The Lynch Lab is always interested in potential new lab members! Please contact Dr. Lynch to learn more about open projects.